实质性地 /ʂɨ́ ʈʂɨ́ ɕìŋ dɨ/ Adverb

English: substantially
Ελληνικά: Σημαντικά

Example

自去年以来，成本已经[相当大地]增加了。
The costs have increased substantially since last year.
强调成本上涨的幅度已经到了一个不可忽视的量级。